Title of article :
Primary amine catalyzed electrophilic amination of α,α-disubstituted aldehydes
Author/Authors :
Desmarchelier، نويسنده , , Alaric and Yalgin، نويسنده , , Hasret and Coeffard، نويسنده , , Vincent and Moreau، نويسنده , , Xavier and Greck، نويسنده , , Christine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Organocatalytic α-amination of α,α-disubstituted aldehydes promoted by 9-amino-(9-deoxy)-epi-quinine is described. α-Hydrazino aldehydes bearing a quaternary stereogenic center are obtained in good to excellent yields and enantioselectivities.
Keywords :
amination , organocatalysis , Primary amine , Quaternary stereocenter , Branched aldehydes
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
