Title of article :
A facile synthesis of spiro macrocarbocycles via the cycloalumination reaction of cyclic alkynes and alkadiynes
Author/Authors :
D’yakonov، نويسنده , , Vladimir A. and Tuktarova، نويسنده , , Regina A. and Khalilov، نويسنده , , Leonard M. and Dzhemilev، نويسنده , , Usein M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Zirconium-catalyzed cycloalumination of cycloalkadiynes assisted by Et3Al, subsequent treatment of the in situ generated tricyclic dialuminum compounds with BrCH2OMe and finally cyclopropanation of the obtained dispiro cyclopropyl dimethylene macrocarbocycles with Et3Al–CH2I2 represents an efficient one-pot synthetic approach to prepare di- and tetraspiro cyclopropane-containing macrocarbocycles in very high yields.
Keywords :
Cyclic diynes , Bis-cyclopropanes , Dzhemilev reaction , Homogeneous catalysis , Organoaluminum compounds , Spiranes , Cycloalumination , Zirconocene dichloride
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
