Title of article
An efficient synthesis of highly functionalized chiral lactams
Author/Authors
Ornelas، نويسنده , , Martha A. and Gonzalez، نويسنده , , Javier and Sach، نويسنده , , Neal W. and Richardson، نويسنده , , Paul F. and Bunker، نويسنده , , Kevin D. and Linton، نويسنده , , Angelica and Kephart، نويسنده , , Susan E. and Pairish، نويسنده , , Mason and Guo، نويسنده , , Chuangxing، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
4760
To page
4763
Abstract
A new method was developed to synthesize highly functionalized lactams via a one pot reductive amination/lactam formation reaction. This methodology is amenable for parallel synthesis and was used to prepare a large number of lactam analogs in a library format with good ee (de) retention.
Keywords
Pantolactone , lactams , Reductive amination/lactam formation
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879213
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