Title of article
Direct one-pot introduction of 2-methylpyridines to Baylis–Hillman adducts via base-mediated 3-aza-Cope rearrangement
Author/Authors
Lee، نويسنده , , Hyun Seung and Lee، نويسنده , , Sangku and Kim، نويسنده , , Se-Hee and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
5039
To page
5042
Abstract
An efficient and regioselective introduction method of 2-methylpyridines to the secondary position of Baylis–Hillman adducts has been developed. A base treatment of 2-methylpyridinium salt of Baylis–Hillman bromide generated N-allylenamine intermediate which underwent a facile 3-aza-Cope rearrangement under mild conditions to produce the product.
Keywords
aza-Cope rearrangement , Baylis–Hillman adducts , 2-Methylpyridines
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879284
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