Title of article :
Asymmetric synthesis of monocyclic β-lactams from l-cysteine using photochemistry
Author/Authors :
Lu، نويسنده , , Xiao-Chun Long، نويسنده , , Timothy E.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An asymmetric method to synthesize cis-configured β-lactams using photochemistry has been developed. Aerobic photo-oxidation of l-cysteine-derived thiazolidine hydroxamate esters afforded C-3 hydroxylated products which when cyclized and deprotected gave the corresponding N-protio monocyclic β-lactams.
Keywords :
?-Lactams , Pummerer rearrangement , Photo-oxidation , Thiazolidines , Hydroxamates
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
