Author/Authors :
Crowley، نويسنده , , Brendan M. and Potteiger، نويسنده , , Craig M. and Deng، نويسنده , , James Z. and Prier، نويسنده , , Christopher K. and Paone، نويسنده , , Daniel V. and Burgey، نويسنده , , Christopher S.، نويسنده ,
Abstract :
Recent advances in the development of the copper facilitated Suzuki–Miyaura reaction are described. Improvements include expansion of substrate scope to include aryl chlorides and polyhalo aryl boronates. It was found that use of S-Phos and X-Phos could accomplish the coupling of 2-pyridyl boronates to aryl chlorides and bromides in shorter reaction times and in higher yield than previously described with DPPF.
Keywords :
Suzuki–Miyaura , 2-Pyridyl boronates , Organometallic , S-Phos , Copper assisted reaction
