Author/Authors :
Lee، نويسنده , , Hee Joon and Park، نويسنده , , Kyungho and Bae، نويسنده , , Goun and Choe، نويسنده , , Jaehoon and Song، نويسنده , , Kwang Ho and Lee، نويسنده , , Sunwoo، نويسنده ,
Abstract :
Unsymmetric diaryl alkynes were synthesized from the palladium-catalyzed decarboxylative coupling of aryl halides and propiolic acid using a continuous flow reaction system. This flow chemistry system continuously gave the desired products in moderate to good yields, and produced less byproduct than was formed in the batch reaction.
Keywords :
Flow chemistry , PALLADIUM , Micromixer , Decarboxylative coupling , Diaryl alkynes