Title of article
A convenient synthesis of new pyrido[3,2-e][1,4]diazepine-2,5-diones and pyrido[2,3-e][1,4]diazepine-2,5-diones
Author/Authors
Abderrahman El Bouakher، نويسنده , , Abderrahman and Laborie، نويسنده , , Hélène and Aadil، نويسنده , , Mina and El Hakmaoui، نويسنده , , Ahmed and Lazar، نويسنده , , Said and Akssira، نويسنده , , Mohamed and Viaud-Massuard، نويسنده , , Marie-Claude، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
5077
To page
5080
Abstract
A convenient synthesis of a series of pyrido[3,2-e][1,4]-diazepine-2,5-diones 8 and pyrido[2,3-e][1,4]diazepine-2,5-diones 9, is reported using the condensation of α-amino acid methyl ester derivatives with 1H-pyrido[3,2-d][1,3]oxazine-2,4-dione and 1H-pyrido[2,3-d][1,3]oxazine-2,4-dione. Compounds 8 and 9 were also synthesized by peptide coupling of α-amino acid methyl ester derivatives with β-amino acids (2 or 3) followed by the cyclisation in tetrahydrofuran with sodium hydride (NaH).
Keywords
4]diazepine-2 , 5-diones , 4]diazipine-2 , 5-diones , Heterocyclization , Azaisatoic anhydride
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879294
Link To Document