Title of article
Thionation of amides using a solid-supported P2S5 reagent under microwave irradiation
Author/Authors
Lagiakos، نويسنده , , Helen Rachel and Walker، نويسنده , , Ashley and Aguilar، نويسنده , , Marie-Isabel and Perlmutter، نويسنده , , Patrick، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
2
From page
5131
To page
5132
Abstract
In this Letter, we describe an improved method for the thionation of amides. Using a solid-supported P2S5 reagent, heating under microwave irradiation furnished thioamides in good to excellent yields, with a significantly reduced reaction time compared with that achieved under conventional heating. Furthermore, a change of solvent from that described in the literature enabled a simplified work-up and purification of the products.
Keywords
microwave irradiation , Phosphorus pentasulfide , thionation , solid-supported reagent
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879308
Link To Document