Title of article :
An efficient one-pot protocol for asymmetric bifunctionalization of 5,15-disubstituted porphyrins: direct access to meso activated alkenyl-substituted meso-formylporphyrins
Author/Authors :
Takanami، نويسنده , , Toshikatsu and Hayashi، نويسنده , , Satoshi and Iso، نويسنده , , Kazuhiro and Matsumoto، نويسنده , , Jun and Hino، نويسنده , , Fumio، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An efficient one-pot protocol for the direct conversion of free base 5,15-disubstituted porphyrins into the corresponding meso activated alkenyl-substituted meso-formylporphyrins has been developed using a sequential SNAr reaction with PyMe2SiCH2Li, conjugate addition to enones or alkenoates in the presence of TMSCl, and oxidation with DDQ.
Keywords :
SNAr reaction , Porphyrin , Silylmethyllithium , ? , ?-unsaturated carbonyl compound
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
