Title of article :
Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini
Author/Authors :
Beattie، نويسنده , , Karren D. and Thompson، نويسنده , , Dion R. and Tiralongo، نويسنده , , Evelin and Ratkowsky، نويسنده , , David and May، نويسنده , , Tom W. and Gill، نويسنده , , Melvyn، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10–31 μg/mL.
Keywords :
Cytotoxic , anthraquinone , Tricolorin , Australian fungi
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
