Title of article :
A novel one-pot synthesis of α-keto-1,3,4-oxadiazole derivatives based on isocyanide-Nef reaction
Author/Authors :
Cui، نويسنده , , Liren and Liu، نويسنده , , Qiong and Yu، نويسنده , , Jingxun and Ni، نويسنده , , Chongzhi and Yu، نويسنده , , Hui، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Various α-keto-1,3,4-oxadiazole derivatives were synthesized through a sequential intermolecular dehydrochlorination/intramolecular aza-Wittig reaction of carboxylic acids and imidoyl chloride intermediates, which were generated by isocyanide-Nef reaction of acyl chlorides and (N-isocyanimine) triphenylphosphorane (1) in CH2Cl2 at room temperature.
Keywords :
Dehydrochlorination , Aza-Wittig condensation , 4 , Isocyanide-Nef reaction , 1 , -Oxadiazole , 3
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
