Author/Authors :
Li، نويسنده , , Ziyuan and Ma، نويسنده , , Ling and Tang، نويسنده , , Changhua and Xu، نويسنده , , Jinyi and Wu، نويسنده , , Xiaoming and Yao، نويسنده , , Hequan، نويسنده ,
Abstract :
Oxidative Heck coupling of thiazole-4-carboxylates via palladium(II)-catalyzed C–H bond activation has been achieved in moderate to good yields. No ligand, and no acidic additive were used in the reaction. The results showed that this protocol tolerated a series of substitutions on the thiazole ring. A preliminary attempt of direct arylation with p-xylene via Pd(II)-catalyzed C–H bond activation has also been done.
Keywords :
C–H bond activation , Thiazole-4-carboxylate , Oxidative Heck-coupling , Direct arylation , Alkenylation
