Title of article :
Suzuki–Miyaura cross-coupling of benzylic bromides under microwave conditions
Author/Authors :
McDaniel، نويسنده , , Steven W. and Keyari، نويسنده , , Charles M. and Rider، نويسنده , , Kevin C. and Natale، نويسنده , , Nicholas R. and Diaz، نويسنده , , Philippe، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A procedure for benzylic Suzuki–Miyaura cross-coupling under microwave conditions has been developed. These conditions allowed for heterocyclic compounds to be coupled. Optimum conditions found were Pd(OAc)2, JohnPhos as the catalyst and ligand, potassium carbonate as the base, and DMF as the solvent. Using these conditions, a library of structurally diverse compounds was synthesized.
Keywords :
PALLADIUM , microwave , cross-coupling , Suzuki–Miyaura
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
