Author/Authors :
Han، نويسنده , , Zhi-Yong and Guo، نويسنده , , Rui and Wang، نويسنده , , Pusheng and Chen، نويسنده , , Dian-Feng and Xiao، نويسنده , , Han-Yuan Gong، نويسنده , , Liu-Zhu، نويسنده ,
Abstract :
An asymmetric cyclization of alkynols triggered addition of azlactones catalyzed by a combined catalyst system consisting of a chiral gold phosphate and a phosphoric acid produces conformationally restricted amino acid precursors bearing vicinal quaternary stereogenic centers in high levels of stereoselectivity.
Keywords :
Relay catalysis , Gold catalyst , Brّnsted acid , Azlactone , Intramolecular hydroalkoxylation
