Title of article
Design of a new oligotriazole peptide nucleic acid analogue (oT-PNA)
Author/Authors
Vergnaud، نويسنده , , Julien and Faugeras، نويسنده , , Pierre-Antoine and Chaleix، نويسنده , , Vincent and Champavier، نويسنده , , Yves and Zerrouki، نويسنده , , Rachida، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
6185
To page
6189
Abstract
We describe in this Letter the synthesis of an original thymine azido-heterotrimer generated by Click Chemistry. This trimer has been obtained from an azido-thymidine and a new chloroethyl-propargylated PNA monomer analogue, after two azidation/click-reaction cycles. Conformational preferences of a rotameric intermediate have also been studied
Keywords
Synthesis design , peptide nucleic acid , click chemistry , Microwave chemistry
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879564
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