Title of article
An efficient synthesis of 2-aminopyrroles from enaminone–amidine adduct and phenacyl/benzyl/heteroalkyl-halides
Author/Authors
Jalani، نويسنده , , Hitesh B. and Pandya، نويسنده , , Amit N. and Baraiya، نويسنده , , Arshi B. and Kaila، نويسنده , , Jitendra C. and Pandya، نويسنده , , Dhaivat H. and Sharma، نويسنده , , Jayesh A. and Sudarsanam، نويسنده , , V. and Vasu، نويسنده , , Kamala K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
5
From page
6331
To page
6335
Abstract
Herein, we report an efficient and facile synthesis of substituted 2-aminopyrroles from the reaction of enaminone–amidine adduct and various phenacyl, benzyl, or heteroalkyl halides in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in good to excellent yields. The reaction proceeds through an intramolecular 5-exo trig cyclization resulting into diversely substituted 2-aminopyrroles.
Keywords
2-Aminopyrroles , Enaminone , Cyanamide , N-Alkylation , 5-Exo trig
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879597
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