Title of article
Reaction between 4-oxoalkane-1,1,2,2-tetracarbonitriles and morpholine: regioselective synthesis of 5-amino-2-(morpholin-4-yl)-3-(2-oxoalkyl)-3H-pyrrol-3,4-dicarbonitriles
Author/Authors
Belikov، نويسنده , , M.Yu. and Ershov، نويسنده , , O.V. and Eremkin، نويسنده , , A.V. and Nasakin، نويسنده , , O.E. and Tafeenko، نويسنده , , V.A. and Nurieva، نويسنده , , E.V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
6407
To page
6410
Abstract
A new approach to the regioselective synthesis of polyfunctional 3H-pyrroles from 4-oxoalkane-1,1,2,2-tetracarbonitriles is described. 5-Amino-3-(2-aryl-2-oxoethyl)-3H-pyrrol-3,4-dicarbonitriles are prepared from 4-aryl-4-oxobutane-1,1,2,2-tetracarbonitriles. Diastereomeric 5-amino-2-morpholin-4-yl-3-(2-oxocyclohexyl)-3H-pyrrole-3,4-dicarbonitriles were obtained from 1-(2-oxocyclohexyl)ethane-1,1,2,2-tetracarbonitriles.
Keywords
deactivation , Cyano groups , 4-Oxoalkane-1 , 1 , 2 , 2-tetracarbonitriles , 3H-Pyrroles
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879617
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