Title of article
Reactivity of 2-formylphenylboronic acid toward secondary aromatic amines in amination–reduction reactions
Author/Authors
Adamczyk-Wo?niak، نويسنده , , Agnieszka and Fratila، نويسنده , , Raluca M. and Madura، نويسنده , , Izabela D. and Pawe?ko، نويسنده , , Alicja and Sporzy?ski، نويسنده , , Andrzej and Tumanowicz، نويسنده , , Marta and Velders، نويسنده , , Aldrik H. and ?y?a، نويسنده , , Jacek، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
6639
To page
6642
Abstract
The synthesis of 2-(arylaminomethyl)phenylboronic acid via an amination–reduction reaction has been investigated within a model system comprising 2-formylphenylboronic acid and N-ethylaniline. Adoption of the appropriate reaction conditions influences the reactivity of 2-formylphenylboronic acid, enabling efficient synthesis of so-far unobtainable 2-(arylaminomethyl)phenylboronic compounds. The first crystal structure of the aromatic amine derivative has been determined and described.
Keywords
Amination–reduction , Benzoxaborole , Aromatic secondary amines , Boronic acids
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879675
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