Author/Authors :
Adamczyk-Wo?niak، نويسنده , , Agnieszka and Fratila، نويسنده , , Raluca M. and Madura، نويسنده , , Izabela D. and Pawe?ko، نويسنده , , Alicja and Sporzy?ski، نويسنده , , Andrzej and Tumanowicz، نويسنده , , Marta and Velders، نويسنده , , Aldrik H. and ?y?a، نويسنده , , Jacek، نويسنده ,
Abstract :
The synthesis of 2-(arylaminomethyl)phenylboronic acid via an amination–reduction reaction has been investigated within a model system comprising 2-formylphenylboronic acid and N-ethylaniline. Adoption of the appropriate reaction conditions influences the reactivity of 2-formylphenylboronic acid, enabling efficient synthesis of so-far unobtainable 2-(arylaminomethyl)phenylboronic compounds. The first crystal structure of the aromatic amine derivative has been determined and described.
Keywords :
Amination–reduction , Benzoxaborole , Aromatic secondary amines , Boronic acids
