Title of article :
Desymmetrization of meso [3.2.1]oxabicyclic systems using metal-catalysed asymmetric intramolecular C–H insertion
Author/Authors :
Zhang، نويسنده , , Xiaomei and Li، نويسنده , , Zhengning and Chu، نويسنده , , John C.K. and Chiu، نويسنده , , Pauline، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Diazoketone derivatives of meso 8-oxabicyclo[3.2.1]octen-3-ones were desymmetrized by an intramolecular C–H insertion mediated by chiral copper and dirhodium catalysts to generate oxatricyclic systems with up to 5 contiguous stereogenic centres and 50% ee.
Keywords :
Carbene , diazo compounds , C–H insertion , desymmetrization , Oxabicyclic compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
