Title of article :
A concise total synthesis of bruceolline E
Author/Authors :
Jordan، نويسنده , , Jason A. and Gribble، نويسنده , , Gordon W. and Badenock، نويسنده , , Jeanese C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
An efficient synthesis of bruceolline E was completed in three steps from the known ethyl indole-1-carboxylate (9d) in 60% overall yield, via a tandem acylation/Nazarov cyclization with 3,3-dimethyl acrylic acid followed by selenium dioxide oxidation to install the α-diketone functionality.
Keywords :
Bruceolline E , Nazarov cyclization , selenium dioxide , indole
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
