Title of article
Improved Hiyama cross-coupling reactions using HOMSi® reagents: a novel application of a palladacycle
Author/Authors
Marcuccio، نويسنده , , Sebastian M. and Epa، نويسنده , , Ruwan and Moslmani، نويسنده , , Maisa and Hughes، نويسنده , , Andrew B.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
7178
To page
7181
Abstract
Various parameters in the Hiyama cross-coupling reaction of HOMSi® reagents with ethyl bromobenzoate were studied. These included solvent, ligand, palladium source, and added water. DMF and THF were found to be excellent solvents. Palladium chloride was found to be the best palladium source and no added water was required. The use of tri-o-tolylphosphine as the ligand proved to be particularly effective.
Keywords
cross-coupling , Hiyama reaction , Tri-o-tolylphosphine , Palladacycle , HOMSi®
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879808
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