Title of article
Copper-catalyzed N-arylation of sulfonamides with aryl bromides under mild conditions
Author/Authors
Wang، نويسنده , , Xiang and Guram، نويسنده , , Anil and Ronk، نويسنده , , Michael and Milne، نويسنده , , Jacqueline E. and Tedrow، نويسنده , , Jason S. and Faul، نويسنده , , Margaret M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
7
To page
10
Abstract
This Letter describes a copper catalyzed sulfonamide coupling reaction with aryl bromides to form N-aryl sulfonamides under mild conditions, including the first examples of Cu-catalyzed sulfonamide coupling at room temperature. The reaction protocol tolerates a broad range of substrates including a variety of primary and secondary sulfonamides and challenging heteroaryl bromides such as 2-bromothiazole.
Keywords
Sulfonamide coupling , Copper catalysis , N-Arylation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1879818
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