Title of article
Synthesis of 2,5-disubstituted-3-cyanoindoles
Author/Authors
Bobko، نويسنده , , Mark A. and Evans، نويسنده , , Karen A. and Kaura، نويسنده , , Arun C. and Shuster، نويسنده , , Leanna E. and Su، نويسنده , , Dai-Shi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
200
To page
202
Abstract
An efficient synthesis of 2,5-disubstituted-3-cyanoindoles is described. This approach utilizes a highly selective iodination together with the modified Madelung reaction to generate an intermediate which can be readily transformed to more fully elaborated 2,5-disubstituted-3-cyanoindole templates that were previously difficult to access. Detailed examples and utility of this approach are presented herein.
Keywords
2 , Modified Madelung reaction , 5-Disubstituted-3-cyanoindoles , selective iodination , Synthesis , 3-Cyanoindoles
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1879899
Link To Document