Author/Authors :
Kissane، نويسنده , , Marie and McNamara، نويسنده , , Orla A. and Mitchell، نويسنده , , David and Coppert، نويسنده , , David M. and Moynihan، نويسنده , , Humphrey A. and Lorenz، نويسنده , , Kurt T. and Maguire، نويسنده , , Anita R.، نويسنده ,
Abstract :
The palladium-catalysed decarboxylative cross-coupling of heterocyclic aromatic carboxylates and aryl halides is described. The cross-coupling proceeds under relatively mild conditions using catalytic Pd(0) and tetrabutylammonium bromide (TBAB). Utilizing a mixed solvent system consisting of N,N-dimethylformamide (DMF) and N-methyl-2-pyrrolidone (NMP), the cross-coupling system operated at temperatures ranging from 80 to 140 °C.
Keywords :
aryl halides , Heterocycles , Biaryls , PALLADIUM , cross-coupling
