Author/Authors :
Chénard، نويسنده , , Sylvain and Barberis، نويسنده , , Claude and Otis، نويسنده , , François and Paquin، نويسنده , , Jean-François and Martel، نويسنده , , Jonathan and Banville، نويسنده , , Charles and Voyer، نويسنده , , Normand، نويسنده ,
Abstract :
We achieved the synthesis of a derivative of phenylalanine with a diazamacrocycle on its side chain by macrocyclization of a dichloride on l-DOPA. We also report its incorporation into peptide structures by solid phase peptide synthesis which will lead to the development of artificial anion channels.
Keywords :
Macrocyclization , anion binding , unnatural amino acid , Diazamacrocycle