• Title of article

    Copper(II)-catalyzed hydration of nitriles with the aid of acetaldoxime

  • Author/Authors

    Ma، نويسنده , , Xiao-Yun and He، نويسنده , , Ying and Hu، نويسنده , , Yu-Lin and Lu، نويسنده , , Ming، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    4
  • From page
    449
  • To page
    452
  • Abstract
    An efficient method for the selective hydration of nitrile to amide by employing inexpensive copper salt catalyst and commercially available acetaldoxime in environmentally friendly water is described. Under this protocol, nitriles including aromatic nitriles, heterocyclic nitriles and aliphatic nitriles were converted into the corresponding amides in good to excellent yields.
  • Keywords
    Acetaldoxime , Hydration , Nitriles , Amides , copper oxide
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2012
  • Journal title
    Tetrahedron Letters
  • Record number

    1880012