Title of article
Copper(II)-catalyzed hydration of nitriles with the aid of acetaldoxime
Author/Authors
Ma، نويسنده , , Xiao-Yun and He، نويسنده , , Ying and Hu، نويسنده , , Yu-Lin and Lu، نويسنده , , Ming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
449
To page
452
Abstract
An efficient method for the selective hydration of nitrile to amide by employing inexpensive copper salt catalyst and commercially available acetaldoxime in environmentally friendly water is described. Under this protocol, nitriles including aromatic nitriles, heterocyclic nitriles and aliphatic nitriles were converted into the corresponding amides in good to excellent yields.
Keywords
Acetaldoxime , Hydration , Nitriles , Amides , copper oxide
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880012
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