Title of article
A convenient synthesis of polysubstituted 2-amino-4,5-dihydrofuran-3-nitriles from benzoins or benzaldehydes
Author/Authors
Du، نويسنده , , Ding and Hu، نويسنده , , Zhongyuan and Tang، نويسنده , , Weifang and Wang، نويسنده , , Bo and Lu، نويسنده , , Tao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
453
To page
457
Abstract
A convenient assembly of polysubstituted 2-amino-4,5-dihydrofuran-3-nitriles from a tandem Michael addition/cyclization reaction between benzoins and arylidenemalononitriles is described. The products are also obtained from readily available benzaldehydes via a sequential N-heterocyclic carbene–catalyzed benzoin condensation and Michael addition/cyclization process in a one-pot tandem procedure.
Keywords
Tandem reactions , Dihydrofurans , Benzoins , Carbenes
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880013
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