Unprecedented syntheses of 1,5-difluoropentan-3-amine and 4-fluoro-2-(2-fluoroethyl)butan-1-amine

Herein, we report two synthetically useful and high yielding routes to so far unknown branched γ,γ′- and δ,δ′-difluoroalkylamines that can be of interest as building-blocks for medicinal chemistry programs.