Efficient and improved synthesis of triazole-linked DNA (TLDNA) oligomers
Author/Authors :
Fujino، نويسنده , , Tomoko G Yamazaki، نويسنده , , Naomi and Hasome، نويسنده , , Ai and Endo، نويسنده , , Kenta and Isobe، نويسنده , , Hiroyuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Pages :
3
From page :
868
To page :
870
Abstract :
A method for the synthesis of triazole-linked DNA oligomers has been revisited to incorporate a reliable protective group and linker for solid-phase synthesis. The new solid-phase synthesis allowed the preparation of oligomers with the efficiency of elongation reaching over 90%.
Keywords :
DNA , oligonucleotides , PROTECTION , solid-phase synthesis
