Title of article
A synthesis of dihydroimidazo[5,1-a]isoquinolines using a sequential Ugi–Bischler–Napieralski reaction sequence
Author/Authors
Seganish، نويسنده , , W. Michael and Bercovici، نويسنده , , Ana and Ho، نويسنده , , Ginny D. and Loozen، نويسنده , , Hubert J.J. and Timmers، نويسنده , , Cornelis M. and Tulshian، نويسنده , , Deen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
903
To page
905
Abstract
A flexible route to analogues of dihydroimidazo[5,1-a]isoquinolines is described. The synthesis hinges on a sequential Ugi coupling, followed by a Bischler–Napieralski reaction to form the imidazole isoquinoline core. This route facilitates the introduction of a range of substitutions throughout the carbon framework.
Keywords
Isoquinoline , Ugi coupling , Bischler–Napieralski
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880123
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