Title of article
Al(OTf)3: an efficient recyclable catalyst for direct nucleophilic substitution of the hydroxy group of propargylic alcohols with carbon- and heteroatom-centered nucleophiles to construct C–C, C–O, C–N and C–S bonds
Author/Authors
Gohain، نويسنده , , Mukut and Marais، نويسنده , , Charlene and Bezuidenhoudt، نويسنده , , Barend C.B.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
1048
To page
1050
Abstract
A general and highly efficient Al(OTf)3-catalyzed methodology has been developed for the direct nucleophilic substitution of the hydroxy group in propargylic alcohols with a variety of carbon- and heteroatom-centered nucleophiles such as alcohols, aromatic compounds, amides, and thiols, leading to the construction of C–C, C–O, C–N and C–S bonds.
Keywords
regioselectivity , Aluminum triflate , Propargylic alcohols , nucleophiles
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880183
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