Title of article :
Rapid access to pyrido[1,2,5]triazepin-4-ones through intramolecular nucleophilic aromatic substitution
Author/Authors :
Jin، نويسنده , , Shujuan and St-Jean، نويسنده , , Olivier and Baltatu، نويسنده , , Sandra I. and Santhakumar، نويسنده , , Vijayaratnam and Tomaszewski، نويسنده , , Miros?aw J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Several 3-substituted pyrido[1,2,5]triazepin-4-ones and their benzo counterparts have been prepared in three steps from commercial starting materials. The key step involves SNAr-type intramolecular nucleophilic aromatic substitution of the appropriate hydrazone substrates.
Keywords :
Heterocycles , Microwave-assisted synthesis , 2 , 5]triazepin-4-ones , ?-ketoamides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
