Author/Authors :
Suzuki، نويسنده , , Yuji and Niwa، نويسنده , , Takanori and Yasui، نويسنده , , Eiko and Mizukami، نويسنده , , Megumi and Miyashita، نويسنده , , Masaaki and Nagumo، نويسنده , , Shinji، نويسنده ,
Abstract :
A tandem reaction consisting of five membered-ring selective Prins cyclization and subsequent Friedel–Crafts cyclization was developed. The reactions of phenyl homoallylic alcohol 3 and benzaldehyde derivatives 6 afforded tetrahydroindenofurans 7 or pentacyclic products 8, depending upon the quantity of 6. Also homoallylic alcohol 12 having an alkyne–cobalt moiety reacted with 6 to give rise to tetrahydroindenofurans 13 in good yields.
Keywords :
Tandem cyclization , Five membered-ring selective Prins cyclization , Friedel–Crafts cyclization , Phenyl homoallylic alcohol , Alkyne–cobalt complex
