Author/Authors :
Hلda، نويسنده , , Magdolna and Nagy، نويسنده , , Veronika and Takلtsy، نويسنده , , Anikَ and Deli، نويسنده , , Jَzsef and Hait، نويسنده , , Jan and Agَcs، نويسنده , , Attila، نويسنده ,
Abstract :
We describe the synthesis of carotenoid derivatives via the azide–alkyne click reaction and optimize the conditions for these sensitive molecules. After finding the mildest conditions possible for the reaction we were able to use the click reaction for the synthesis of PEG–carotenoid conjugates starting from carotenoid pentynoates and PEG azides.
Keywords :
Ester , carotenoid , Azide–alkyne click reaction , PEG conjugates