Author/Authors :
Basilio-Lopes، نويسنده , , Alexandra and de Aquino، نويسنده , , Thiago Mendonça and Mongeot، نويسنده , , Alexandre and Bourguignon، نويسنده , , Jean-Jacques and Schmitt، نويسنده , , Martine، نويسنده ,
Abstract :
A convenient and general method of preparation of polyfunctionalized imidazo[1,2-a]pyridines is reported. This methodology involves activation of secondary amides leading to the formation of the corresponding amidines 9. Different activating reagents have been evaluated and the efficiency of PCl5 was illustrated with alkyl functionalized groups.
Keywords :
PCl5 , 2-a]pyridine , Amidines , TiCl4
