Title of article :
Aspergilazine A, a diketopiperazine dimer with a rare N-1 to C-6 linkage, from a marine-derived fungus Aspergillus taichungensis
Author/Authors :
Cai، نويسنده , , Shengxin and Kong، نويسنده , , Xianglan and Wang، نويسنده , , Wei and Zhou، نويسنده , , Huinan and Zhu، نويسنده , , Tianjiao and Li، نويسنده , , Dehai and Gu، نويسنده , , Qianqun، نويسنده ,
Abstract :
A novel diketopiperazine (DKP) dimer, aspergilazine A (1), dimerized by two DKP units via a rare N-1 to C-6 linkage, was isolated from the marine-derived fungus Aspergillus taichungensis ZHN-7-07. The structure was determined by the combination of spectroscopic and Marfey’s methods. Biological evaluation indicated that aspergilazine A (1) had a weak activity against influenza A (H1N1) virus.
Keywords :
Aspergilazine A , Diketopiperazine dimer , Aspergillus taichungensis , antiviral activity
