Solvent dependency of the yield of an N-monosubstituted diaziridine: a GC–MS study

Due to the growing importance of diaziridines in the drug design and the increasing popularity of diazirines as carbene precursors, the solvent influence on the yield of an N-monosubstituted diaziridine has been studied. It was observed that data points within every solvent class are clustering and the yield in general is the highest in apolar aprotic solvents.