Title of article
Kanamycin A 6′-pyrenylamide: a selective probe for heparin detection
Author/Authors
S.R. Nalage، نويسنده , , Santosh V. and Bhosale، نويسنده , , Sidhanath V. and Bhargava، نويسنده , , Suresh K. and Bhosale، نويسنده , , Sheshanath V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
2864
To page
2867
Abstract
We have synthesized a novel derivative of kanamycin A bearing a pyrenyl fluorophore which can be used for the specific recognition of heparin in EtOH:H2O (1:3) through formation of a 2:1 complex. The receptor shows specific optical signalling for heparin, but exhibits no significant changes on addition of various other biological molecules.
Keywords
Pyrene , HEPARIN , fluorescence , UV–vis spectroscopy , aminoglycoside , Biosensor
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880874
Link To Document