Title of article
Acremolin, a new 1H-azirine metabolite from the marine-derived fungus Acremonium strictum
Author/Authors
Julianti، نويسنده , , Elin and Oh، نويسنده , , Hana and Lee، نويسنده , , Hyi-Seung and Oh، نويسنده , , Dong-Chan and Oh، نويسنده , , Ki-Bong and Shin، نويسنده , , Jongheon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
2
From page
2885
To page
2886
Abstract
Acremolin (1), a novel modified base, was isolated from the culture broth of the marine fungus Acremonium strictum. Based on combined spectroscopic analyses, the structure of this compound was that of a methyl guanine base containing an isoprene unit. In addition, the presence of a 1H-azirine moiety is unprecedented among natural products. This compound exhibited weak cytotoxicity against an A549 cell line.
Keywords
A modified base , 1H-Azirine functionality , Acremonium strictum , Marine fungus , Acremolin
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880883
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