Title of article
Highly chemoselective palladium-catalyzed Sonogashira coupling of 5-iodouridine-5′-triphosphates with propargylamine: a new efficient method for the synthesis of 5-aminopropargyl-uridine-5′-triphosphates
Author/Authors
Kore، نويسنده , , Anilkumar R. and Senthilvelan، نويسنده , , Annamalai and Shanmugasundaram، نويسنده , , Muthian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
3070
To page
3072
Abstract
An efficient palladium-catalyzed Sonogashira coupling of 5-iodouridine-5′-triphosphates with propargylamine is described. The catalytic reaction is highly chemoselective that affords exclusively 5-aminopropargyl-uridine-5′-triphosphates in good yields with high purities (>99.8%).
Keywords
Sonogashira-coupling , Chemoselective , Aminopropargyl nucleotides , PALLADIUM , Non-radioactive probe
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880958
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