Title of article :
CuCN catalyzed one pot synthesis of γ-keto diesters: domino double Michael addition followed by Nef reaction
Author/Authors :
Farooq، نويسنده , , Saleem and Sangwan، نويسنده , , Payare L. and Aleti، نويسنده , , Rajeshwar R. and Chinthakindi، نويسنده , , Praveen K. and Qurishi، نويسنده , , Mushtaq A. and Koul، نويسنده , , Surrinder، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Pages :
5
From page :
3305
To page :
3309
Abstract :
An efficient one pot synthesis of γ-keto diesters through double Michael addition coupled with Nef reaction in the presence of CuCN catalyst and Cs2CO3 base is described. The reaction proceeds rapidly in DCM to give the products in good yields. A plausible mechanism is proposed.
Keywords :
Nef reaction , ?-Keto diesters , Copper cyanide , Michael reaction
Journal title :
Tetrahedron Letters
Serial Year :
2012
Journal title :
Tetrahedron Letters
Record number :
1881046
Link To Document :
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