Title of article
Enantio- and diastereoselective Michael addition reactions of α-cyanoketones to nitroalkenes catalyzed by binaphthyl-derived organocatalyst
Author/Authors
Lee، نويسنده , , Hyun Joo and Woo، نويسنده , , Saet Byeol and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3374
To page
3377
Abstract
The catalytic enantioselective and diastereoselective Michael addition reactions promoted by chiral bifunctional organocatalysts are described. The treatment of α-cyanoketones with nitroalkenes under mild reaction conditions afforded the corresponding γ-niro α-cyanoketones with excellent diastereoselectivities (up to syn/anti >99/1) and excellent enantioselectivities (up to 99% ee).
Keywords
organocatalysis , Michael reaction , Asymmetric catalysis , Cyanoketones , Nitroalkenes
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881072
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