Title of article :
A one-pot, three-component synthesis of thiazolidine-2-thiones
Author/Authors :
Ziyaei-Halimehjani، نويسنده , , Azim and Marjani، نويسنده , , Katayoun and Ashouri، نويسنده , , Akram، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
An efficient method for the synthesis of thiazolidine-2-thiones is described via regiospecific iodocyclization of an allyl amine, carbon disulfide, and iodine. Dehydrohalogenation of the iodo-derivatives gives thiazole-2(3H)-thiones. In addition, nucleophilic substitution of the iodine in the products is accomplished using NaN3, thiophenol, or dithiocarbamate.
Keywords :
regiospecific , iodocyclization , Thiazolidine-2-thione , Dehydrohalogenation , nucleophilic substitution
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters