Title of article :
Cannabisol, a novel Δ9-THC dimer possessing a unique methylene bridge, isolated from Cannabis sativa
Author/Authors :
Zulfiqar، نويسنده , , Fazila and Ross، نويسنده , , Samir A. and Slade، نويسنده , , Desmond and Ahmed، نويسنده , , Safwat A. and Radwan، نويسنده , , Mohamed M. and Ali، نويسنده , , Zulfiqar and Khan، نويسنده , , Ikhlas A. and ElSohly، نويسنده , , Mahmoud A.، نويسنده ,
Abstract :
Cannabisol (1), a unique dimer of Δ9-tetrahydrocannabinol (Δ9-THC) with a methylene bridge, was isolated from Cannabis sativa. This is the first example of a C-bridged dimeric cannabinoid. The structure of 1 was unambiguously deduced by HRESIMS, GCMS, and NMR spectroscopy. A plausible biogenesis of 1 is described.
