Title of article
Cu(I)/DTBM-BIPHEP-catalyzed exo-selective 1,3-dipolar cycloaddition of azomethine ylides with cis-trifluorocrotonate for asymmetric construction of trifluoromethylated pyrrolidines
Author/Authors
Li، نويسنده , , Qing-Hua and Xue، نويسنده , , Zhi-Yong and Tao، نويسنده , , Hai-Yan and Wang، نويسنده , , Chun-Jiang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3650
To page
3653
Abstract
A direct and facile access to highly substituted exo-pyrrolidines bearing a unique trifluoromethyl group is developed via Cu(I)/DTBM-BIPHEP-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with cis-4,4,4-trifluorocrotonate for the first time.
Keywords
stereoselectivity , pyrrolidine , Asymmetric catalysis , Trifluoromethyl group , 1 , 3-dipolar cycloaddition
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881195
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