Title of article
Catalytic enantioselective chlorination of cyclic β-keto esters in the presence of chiral Pd(II) complexes
Author/Authors
Kang، نويسنده , , Young Ku and Kim، نويسنده , , Hee Hun and Koh، نويسنده , , Kwang Oh and Kim، نويسنده , , Dae Young، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3811
To page
3814
Abstract
The catalytic enantioselective electrophilic chlorination promoted by chiral palladium complexes is described. The treatment of β-keto esters with 2,3,4,5,6,6-hexachlorocyclohex-2,4-dienone as chlorine source under mild reaction conditions afforded the corresponding α-chlorinated β-keto esters with excellent enantioselectivities (up to 94% ee).
Keywords
Chiral palladium catalysts , Chlorination , Asymmetric catalysis , ?-keto esters
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881266
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