Title of article
An unexpected route toward the synthesis of spiro-benzo[b]acridine-furan derivatives
Author/Authors
Ghadari، نويسنده , , Rahim and Hajishaabanha، نويسنده , , Fatemeh and Mahyari، نويسنده , , Mojtaba and Shaabani، نويسنده , , Ahmad and Khavasi، نويسنده , , Hamid Reza، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4018
To page
4021
Abstract
A facile and straightforward procedure for the synthesis of spiro-benzo[b]acridine-6,2′-furan derivatives via the reaction between benzo[b]acridine-6,11-dione, electron-deficient acetylenic compounds, and an isocyanide is described. The benzo[b]acridine-6,11-dione is obtained from the reaction between 2-(aminomethyl)aniline and 2-hydroxynaphthalene-1,4-dione via an unexpected reaction pathway. The products are synthesized in medium to high yields and no complicated purification is required.
Keywords
heterocycle , hetero-Diels–Alder , isocyanide , multicomponent reaction , 2?-furan
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881355
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