Title of article
An efficient, greener, and solvent-free one-pot multicomponent synthesis of 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H)ones
Author/Authors
Jalani، نويسنده , , Hitesh B. and Pandya، نويسنده , , Amit N. and Pandya، نويسنده , , Dhaivat H. and Sharma، نويسنده , , Jayesh A. and Sudarsanam، نويسنده , , V. and Vasu، نويسنده , , Kamala K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
4062
To page
4064
Abstract
Herein, we report an efficient, greener, and solvent-free novel method for the synthesis of 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H)ones in a one-pot sequence using methyl anthranilate or 2-aminothiophene-3-carboxylate with N,N′-dimethyl formamide dimethyl acetal and various anilines. The driving force for this reaction is the removal of N,N′-dimethylamine by various anilines resulting in 3-substituted quinazolin-4(3H)ones and thienopyrimidin-4(3H)ones.
Keywords
3-Substituted-quinazolin-4(3H)ones , 3-Substituted-thienopyrimidin-4(3H)ones , Greener approach , formamidine , One pot reaction
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881375
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