Title of article :
Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling
Author/Authors :
Paul، نويسنده , , Sibasish and Nandi، نويسنده , , Bappaditya and Pattanayak، نويسنده , , Sankha and Sinha، نويسنده , , Surajit، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in good to excellent yields (67–86%). We have optimized the iodination conditions for the preparation of 5-iodo uracil–morpholino monomer under basic condition.
Keywords :
Uracil–morpholino , iodination , detritylation , Sonogashira coupling , Alkynyl-derivatives
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
